Investigation of Outpatient PUlmonary REhabilitation in Patients Suffering From Post-PE Syndrome: a Randomized Waitlist-controlled Trial - the PURE-PE Study
This study is a multicenter, parallel, randomized waitlist-controlled trial that primarily focuses on the short-term benefit of outpatient pulmonary rehabilitation (PR) on patients after acute pulmonary embolism. Patients will be randomized into an intervention and a control group. The intervention group will receive 6 weeks of outpatient PR, while patients in the other treatment arm will serve as a control. After completion of the randomized study, the second arm will undergo PR as well.
• Post-PE syndrome (except patients previously diagnosed with CTEPH) diagnosed by any of the following:
‣ Post-PE functional impairment criteria
⁃ Post-PE Cardiac Impairment criteria
⁃ Chronic Thromboembolic Disease criteria
• Possibility of starting rehabilitation between 12 and 36 weeks after the initial event of PE